ZW10 抗体
Quick Overview for ZW10 抗体 (ABIN7121086)
抗原
See all ZW10 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ZW10 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ZW10, kinetochore associated, homolog(Drosophila)
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ZW10 (Zw10 Kinetochore Protein (ZW10))
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别名
- ZW10
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背景
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Synonyms: Centromere/kinetochore protein zw10 homolog|ZW10
Background: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex(PubMed:11590237, PubMed:15485811, PubMed:15824131). Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum(ER), the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER(PubMed:15029241).
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分子量
- 90 kDa
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基因ID
- 9183
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UniProt
- O43264
抗原
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